The "top-down" shoot-em-up Zombies Ate My Neighbors was a favorite of the 16-bit era and not even the sole classic to come out of LucasArts in 1993. It is also, seemingly, among the most sequelizable games ever made.
Despite this, its potential as a series has been weirdly explored. It did get one official sequel, Ghoul Patrol, but that apparently began as an unrelated game only to be redecorated as a Zombies follow-up at the eleventh hour. A spiritual successor, Herc's Adventures was made by key members of the Zombies team but is technically not part of the brand, even if the branding is all that's missing.
Two obscure successors always seemed to be a rather limp legacy for a game that is still so fondly remembered, and apparently there are some developers that agree. Enter Demons Ate My Neighbors! by Tuned-Out Games and HumaNature Studios. Says Nintendo Enthusiast:
The premise of the game is a cursed VHS tape has turned Fairweather Valley into “a den of horrors,” ruining April and Joey’s relaxing summer. Now it’s up to them to use squirt guns filled with holy water to save everyone, while also battling creatures inspired by classic horror films.
If the title and premise don't convince you that this title is explicitly intended as an unambiguous tribute to Zombies Ate My Neighbors, the screenshot in the full write-up will. Look for Demons Ate My Neighbors! on Nintendo Switch and PC sometime in 2021, preferably with a Player 2 on hand.
Source: Nintendo Enthusiast