Remember that interview that said that Telltale is working with Warner Bros. to release Poker Night at the Inventory in 2013? It seems like there might be something to it after all.
There are some items released in the latest Team Fortress 2 update that contain the PN2 prefix. Softpedia and a smattering of fans think they are related to a Poker Night 2, since they contain the PN2 prefix. The items are Sam's hat from Sam & Max, Handsome Jack's mask from Borderlands 2, Ash's crown from Evil Dead, Chell's boots from Portal, and Brock Samson's knife from Venture Bros.
But that's not the only piece that fits into the Poker Night 2 puzzle. "Poker Night 2 Early Access Comp" has been added to the Steam Database. Additionally, a Steam Group for the game's id is available, but not yet active.
So it does seem like we'll be getting a sequel to Telltale Texas Hold'em's spiritual sequel soon.